Proton Pump Inhibitors prescribed for Acid Reflux/GERD Could Increase Your Risk of Osteoporosis

Once a person is diagnosed with gastroesophageal reflux disease or GERD their physician may prescribe Proton pump inhibitors. These include esomeprazole (Nexium), lansoprazole (Prevacid), omeprazole (Prilosec), pantoprazole (Protonix), rabeprazole (AcipHex), dexlansoprazole (Kapidex, approved in 2009), and an omeprazole/ sodium bicarbonate combination (Zegerid) which are the utmost potent suppressors of gastric acid secretion.  However, these may not be a good alternative to lifestyle changes to alleviate the symptoms (Johns Hopkins Health Alert).

The Food and Drug Administration (FDA) issued a warning in May 2010 of PPI use and hip fractures due togrowing concerns regarding long-term PPI use and the risk of hip fractures. The researchers conducted by Massachusetts General Hospital, took into account several factors, such as alcohol intake, body weight, duration of physical activity, smoking status, calcium supplement usage, and menopausal status.

According to Digestive Health, “A 2008 study found that among 63,000 adults over age 50, the 15,792 who had an osteoporosis-related fracture, were twice as likely to have used the medication for at least seven years”.  In addition, consider that most people plan on taking PPIs for long term use so the risks are increased with continuous consumption.